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CDC Emerging Infectious Diseases Seroprevalence of Heartland Virus Antibodies in Blood Donors, Northwestern Missouri, USA Feb 2019 Estimated the seroprevalence of Heartland virus antibodies is 0.9% in a sample of blood donors from northwestern Missouri, … where human cases and infected ticks have been identified. Although these findings suggest that some past human infections were undetected, the estimated prevalence is low. https://wwwnc.cdc.gov/eid/article/25/2/181288_article